R. M. Wang

Extracellular matrix and cyclic stretch alter fetal cardiomyocyte proliferation and maturation in a rodent model of heart hypoplasia

This study investigates how extracellular matrix and cyclic stretch affect cardiomyocyte proliferation and maturation in a rodent model of heart hypoplasia, finding that hypoplastic cardiomyocytes remain immature and show altered responses to mechanical cues.

Immunomodulatory Contribution of Mast Cells to the Regenerative Biomaterial Microenvironment

This study shows mast cells regulate immune response to regenerative biomaterials, with sex-specific effects on macrophage polarization and inflammation.

Myocardial matrix material supports a proliferative microenvironment for cardiomyocytes

This study shows that myocardial matrix hydrogel promotes cardiomyocyte proliferation by scavenging ROS and supporting cell cycle progression in vitro and in vivo.