BiochemistrybioRxiv
OTUB1 is a key regulator of RIG-I dependent immune signalling and is targeted for proteasomal degradation by influenza A NS1
A. S. Jahan, E. Biquand, R. Munoz-Moreno…·S. Sanyal
This study identifies OTUB1 as a regulator of RIG-I immune signaling, showing it is degraded by influenza NS1 to suppress antiviral responses.
DOI 10.1016/j.celrep.2020.01.015