Author

C. K.-P. Mok

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

L. L. M. Poon· 2 shared S. Sanyal· 2 shared A. Chin· 1 shared A. Garcia-Sastre· 1 shared A. Le Quang· 1 shared A. S. Jahan· 1 shared A. te Velthuis· 1 shared B. Zee· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

L. L. M. Poon

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3 papers

Recent·Most cited

Predictive evolutionary modelling for influenza virus by site-based dynamics of mutations

J. Lou, W. Liang, L. Cao, S. Zhao, Z. Chen, R. W. Chan, P. P. H. Cheung, H. Zheng, C. Liu, Q. Li, M. Chong, Y. Zhang, E.-k. Yeoh, P. K. Chan, B. Zee, , M. H. Wang

A computational model predicts influenza virus evolution and aids in vaccine strain selection by modeling site-wise mutation dynamics.

bioRxiv · Aug 23, 2023Evolutionary Biology

Mutation nsp6 L232F associated with MERS-CoV zoonotic transmission confers higher viral replication in human respiratory tract cultures ex-vivo

R. T. So, D. K. W. Chu, K. P. Y. Hui, C. K.-P. Mok, S. Sanyal, J. M. Nicholls, J. C. W. Ho, M. C. Cheung, K. C. NG, H. W. Yeung, M. C. W. Chan, L. L. M. Poon, J. Zhao, J. S. M. Peiris

This study identifies the nsp6 L232F mutation in MERS-CoV as enhancing viral replication in human respiratory tissues and mice, suggesting a role in human adaptation.

bioRxiv · Mar 27, 2023Microbiology

OTUB1 is a key regulator of RIG-I dependent immune signalling and is targeted for proteasomal degradation by influenza A NS1

A. S. Jahan, E. Biquand, R. Munoz-Moreno, A. Le Quang, C. K.-P. Mok, H. H. Wong, Q. W. Teo, S. Doak, A. Chin, L. L. M. Poon, A. te Velthuis, A. Garcia-Sastre, C. Demeret, S. Sanyal

This study identifies OTUB1 as a regulator of RIG-I immune signaling, showing it is degraded by influenza NS1 to suppress antiviral responses.

bioRxiv · May 15, 2019Biochemistry