Author

R. P. Mukku

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

T. R. Raghunand· 3 shared P. Kokavalla· 2 shared C. V. Yeruva· 1 shared K. Chakraborty· 1 shared M. Savanagouder· 1 shared N. Nagarajan· 1 shared S. Yadav· 1 shared U. Kiran· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

9 top collaborators · 20 mutual co-author links

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3 shared papersMicrobiology

T. R. Raghunand

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The PPE25 (Rv1787)-PE18 (Rv1788)-PPE26 (Rv1789) gene cluster is involved in immune evasion by Mycobacterium tuberculosis

R. P. Mukku, P. Kokavalla, K. Chakraborty, T. R. Raghunand

This study identifies the PPE25-PE18-PPE26 gene cluster in Mycobacterium tuberculosis as involved in immune evasion by modulating cytokine levels and macrophage responses.

bioRxiv · Apr 7, 2023 · PreprintMicrobiology

Dissecting the Ca2+ dependence of Mycobacterium tuberculosis DesA1 function

M. Savanagouder, R. P. Mukku, U. Kiran, C. V. Yeruva, N. Nagarajan, Y. Sharma, T. R. Raghunand

This study investigates the role of Ca2+ in Mycobacterium tuberculosis DesA1 function, showing that Ca2+ binding stabilizes the protein and is essential for its activity and resistance to isoniazid.

bioRxiv · Mar 31, 2023 · PreprintMicrobiology

Delineating the functional role of the PPE50 (Rv3135) - PPE51 (Rv3136) gene cluster in the pathophysiology of Mycobacterium tuberculosis

R. P. Mukku, P. Kokavalla, S. Yadav, T. R. Raghunand

This study identifies the PPE50-PPE51 gene cluster in M. tuberculosis as promoting bacillary persistence through TLR1-dependent immunomodulation, reducing intracellular viability and increasing anti-inflammatory cytokine levels.

bioRxiv · Mar 30, 2023 · PreprintMicrobiology