N. Nagarajan

Life stage impact on the human skin ecosystem: lipids and the microbial community

The paper investigates how life stages affect the human skin microbiome and lipid mediators, finding microbial correlations with lipid profiles and cytokine production.

Comparison of tet(X4)-containing contigs from metagenomic sequencing data with plasmid sequences of isolates from a cohort of healthy subjects.

This study compares tet(X4)-containing contigs from metagenomic data with plasmid sequences from isolates in a healthy cohort, finding high similarity and co-occurrence of resistance genes.

Tip of the iceberg? Three novel TOPLESS interacting effectors of the gall-inducing fungus Ustilago maydis

The paper identifies three novel effector proteins from Ustilago maydis that interact with maize TPL proteins and modulate auxin signaling, contributing to fungal virulence.

Dissecting the Ca2+ dependence of Mycobacterium tuberculosis DesA1 function

This study investigates the role of Ca2+ in Mycobacterium tuberculosis DesA1 function, showing that Ca2+ binding stabilizes the protein and is essential for its activity and resistance to isoniazid.

16S rRNA sequencing for profiling microbial communities in idiopathic granulomatous mastitis

This study uses 16S rRNA sequencing to compare microbial communities in IGM and LM patients, finding distinct profiles but no specific pathogen.

No evidence for a common blood microbiome based on a population study of 9,770 healthy humans

This study analyzes blood microbiome data from 9,770 healthy humans and finds no evidence of a common or consistent blood microbiome.

Genomic patterns of divergence in the early and late steps of speciation of the deep-sea vent thermophilic worms of the genus Alvinella.

This study examines genomic divergence patterns in early and late speciation stages of deep-sea vent worms, finding that early divergence involves scattered genes while late stages show genome-wide divergence linked to habitat specialization.

Whole-genome analysis of antimicrobial-resistant Escherichia coli in human gut microbiota reveals its origin and flexibility in transmitting mcr-1

This study analyzes MDR E. coli from human gut microbiota, revealing high diversity, virulence gene variation, and potential transmission from raw meat.

Direct RNA sequencing reveals structural differences between transcript isoforms

This study introduces PORE-cupine, a method combining structure probing and nanopore sequencing to detect RNA secondary structures, revealing isoform-specific structural differences and their impact on translation efficiency.

Cartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environment

The paper characterizes antibiotic resistance genes and opportunistic pathogens in a hospital environment using genomic sequencing and identifies multidrug-resistant strains persisting for over 8 years.

Single-Virion Sequencing Of Lamivudine Treated HBV Populations Reveal Population Evolution Dynamics And Demographic History

This study uses single-virion sequencing to analyze HBV population dynamics in treated patients, revealing selective sweeps and demographic history.