Pharmacology & ToxicologyEnvironmental PollutionPeer-reviewed
Pharmacological inhibition of PAI-1 alleviates cardiopulmonary pathologies induced by exposure to air pollutants PM2.5
A. K. Ghosh, S. Soberanes, E. Lux…·D. E. Vaughan
This study shows that inhibiting PAI-1 with TM5614 reduces PM2.5-induced cardiopulmonary and vascular damage in both in vivo and in vitro models.
DOI 10.1016/j.envpol.2021.117283