Pharmacological inhibition of PAI-1 alleviates cardiopulmonary pathologies induced by exposure to air pollutants PM2.5
A. K. Ghosh, S. Soberanes, E. Lux, M. Shang, R. Piseaux Aillon, M. Eren, G. R. S. Budinger, T. Miyata, D. E. Vaughan
This study shows that inhibiting PAI-1 with TM5614 reduces PM2.5-induced cardiopulmonary and vascular damage in both in vivo and in vitro models.
Environmental Pollution · Oct 1, 2021Peer-reviewedPharmacology & Toxicology