Author

A. K. Ghosh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

A. T. Raman· 2 shared E. Orouji· 2 shared J. Schulz· 2 shared K. Rai· 2 shared M. Maitituoheti· 2 shared M. Tang· 2 shared A. Azhdarnia· 1 shared A. K. Singh· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

A. T. Raman

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Author profile →

3 papers

Recent·Most cited

Pharmacological inhibition of PAI-1 alleviates cardiopulmonary pathologies induced by exposure to air pollutants PM2.5

A. K. Ghosh, S. Soberanes, E. Lux, M. Shang, R. Piseaux Aillon, M. Eren, G. R. S. Budinger, T. Miyata, D. E. Vaughan

This study shows that inhibiting PAI-1 with TM5614 reduces PM2.5-induced cardiopulmonary and vascular damage in both in vivo and in vitro models.

Environmental Pollution · Oct 1, 2021Peer-reviewedPharmacology & Toxicology

H3K4me1-marked Enhancer Activation in Resistant Prostate Cancers Implicates SOX4 and MENIN Inhibition as Therapeutic Strategies

C. Terranova, M. Maitituoheti, A. T. Raman, M. Tang, N. E. Anvar, A. K. Ghosh, S. B. Amin, J. Schulz, E. Orouji, F. Giancotti, P. Troncoso, C. J. Logothetis, T. Thompson, K. Rai

The paper identifies H3K4me1-marked enhancers in therapy-resistant prostate cancers and suggests SOX4 and MENIN inhibition as therapeutic strategies.

bioRxiv · Sep 2, 2021 · PreprintCancer Biology

Chromatin State Dynamics Confers Specific Therapeutic Strategies in Enhancer Subtypes of Colorectal Cancer

E. Orouji, A. T. Raman, A. K. Singh, A. Sorokin, E. Arslan, A. K. Ghosh, J. Schulz, C. J. Terranova, M. Tang, M. Maitituoheti, S. C. Callahan, K. J. Tomczak, Z. Jiang, J. S. Davis, S. Ghosh, , K. Rai

This study identifies enhancer subtypes in colorectal cancer through epigenomic analysis and proposes targeted therapeutic strategies based on these subtypes.

bioRxiv · Sep 4, 2020Cancer Biology