R. R. Gudi

Engineered dendritic cells expressing checkpoint receptor ligands reduce insulitis and hyperglycemia in NOD mice by enhancing regulatory T cell responses and suppressing effector T cell function.

This study shows that Gastrin-producing mesenchymal stem cells protect NOD mice from type 1 diabetes by preserving beta-cell mass and modulating immune responses.

This study shows that gut microbiota influences intestinal immune responses and autoimmune progression differently in male and female lupus-prone mice, with gender-specific effects on disease susceptibility.

This study shows engineered dendritic cells expressing multiple T cell inhibitory ligands induce CD4+ T cell tolerance and suppress autoimmunity.

This study shows that mucosal and systemic exposures to Bacteroides fragilis have opposing effects on type 1 diabetes in NOD mice, with polysaccharide-A playing a key role.

This study shows that oral administration of yeast β-glucan modulates gut immune function, microbiota, and delays type 1 diabetes in NOD mice.