Author

R. Ruiz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Biophysics· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. D. MacKerell· 1 shared A. des Georges· 1 shared A. Grishaev· 1 shared A. Krsitopeit· 1 shared A. Martinez· 1 shared A. Pollock· 1 shared A. Read· 1 shared B. Auriol· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiophysics

A. D. MacKerell

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

An oral protein cocktail therapeutic for C. difficile infection

H. Zhao, M. Dodds, A. Pollock, M. Gewe, A. Martinez, K. Keeney, B. Jester, M. Hutton, H. Tabakh, M. Zhang, M. Heinnickel, T. Paddock, S. Ertel, K. Aggarwal, C. Amendola, , Guzma

This paper describes an oral protein cocktail, LMN-201, for C. difficile infection, showing it achieves high cure rates and validates spirulina as a delivery platform.

bioRxiv · Dec 21, 2021 · PreprintBioengineering

Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a novel macromolecular assembly

X. Xu, R. Ruiz, K. A. Adipietro, C. Peralta, D. Ben-Hail, K. M. Varney, M. E. Cook, B. M. Roth, P. T. Wilder, T. Cleveland, A. Grishaev, H. Neu, S. Michel, W. Yu, D. Beckett, , D. J. Weber

This paper determines the atomic structures of the C. difficile binary toxin CDTb using cryoEM and X-ray crystallography, revealing novel di-heptamer forms and critical domains for toxicity and stability.

bioRxiv · Nov 10, 2019 · PreprintBiophysics

Overt and covert paths for sound in the auditory system of mammals

B. M. Auriol, B. Auriol, J. Beard, B. Bibe, J.-M. Broto, D. Descouens, L. J. Durand, J.-P. Florens, F. Garcia, E. Joiner, B. Libes, P. Pergent, R. Ruiz, C. Thalamas

The paper proposes and experimentally supports a bioelectronic pathway for high-frequency sound transmission in mammals, complementing the traditional mechanical pathway.

bioRxiv · Mar 18, 2019 · PreprintPhysiology