Author

R. S. Zou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Marin-Gonzalez· 2 shared T. Ha· 2 shared Y. Liu· 2 shared B. J. Mog· 1 shared F. Aviles-Vazquez· 1 shared H. B. Liu· 1 shared J. X. J. Luo· 1 shared L. L. Shen· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

A. Marin-Gonzalez

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Author profile →

2 papers

Recent·Most cited

Improving the sensitivity of in vivo CRISPR off-target detection with DISCOVER-Seq+

R. S. Zou, Y. Liu, O. E. Reyes Gaido, M. F. Konig, B. J. Mog, L. L. Shen, F. Aviles-Vazquez, A. Marin-Gonzalez, T. Ha

DISCOVER-Seq+ improves CRISPR off-target detection sensitivity by using DNA-PKcs inhibition and ChIP-seq to identify more off-target sites in cells and mice.

bioRxiv · Oct 29, 2022Bioengineering

Massively parallel genomic perturbations with multi-target CRISPR reveal new insights on Cas9 activity and DNA damage responses at endogenous sites

R. S. Zou, A. Marin-Gonzalez, Y. Liu, H. B. Liu, L. Shen, R. Dveirin, J. X. J. Luo, R. Kalhor, T. Ha

This paper introduces multi-target gRNAs (mgRNAs) to enable high-throughput CRISPR screening, revealing insights into Cas9 dynamics, DNA damage responses, and chromatin changes at endogenous sites.

bioRxiv · Jan 18, 2022 · PreprintCell Biology