H. B. Liu

The Plasmodium falciparum apicoplast cysteine desulfurase provides sulfur for both iron sulfur cluster assembly and tRNA modification

This study identifies the dual role of Plasmodium falciparum SufS in providing sulfur for both FeS cluster assembly and tRNA modification in the apicoplast.

Massively parallel genomic perturbations with multi-target CRISPR reveal new insights on Cas9 activity and DNA damage responses at endogenous sites

This paper introduces multi-target gRNAs (mgRNAs) to enable high-throughput CRISPR screening, revealing insights into Cas9 dynamics, DNA damage responses, and chromatin changes at endogenous sites.