Author

R. Skotheim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 2 Approach:experimental assay· 2 Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1

Frequent Co-Authors

A. J. Borst· 2 shared D. Baker· 2 shared A. Broerman· 1 shared A. Hand· 1 shared A. Idris· 1 shared A. Khmelinskaia· 1 shared A. Philomin· 1 shared A. Pillai· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

A. J. Borst

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

De novo design of allosterically switchable protein assemblies

A. Pillai, A. Idris, A. Philomin, C. Weidle, R. Skotheim, P. J. Y. Leung, A. Broerman, C. Demakis, A. J. Borst, F. Praetorius, D. Baker

This paper designs allosterically switchable protein assemblies using rigid-body coupling of effector-switchable modules, demonstrating cooperative ligand binding and structural changes similar to natural systems.

bioRxiv · Nov 1, 2023Biochemistry

Computational design of non-porous, pH-responsive antibody nanoparticles

E. C. Yang, R. Divine, M. C. Miranda, A. J. Borst, W. Sheffler, J. Z. Zhang, J. Decarreau, A. Sarajovi, M. Abedi, N. Goldbach, M. Ahlrichs, C. Dobbins, A. Hand, S. Cheng, M. Lamb, , D. Baker

This paper designs pH-responsive antibody nanoparticles with three distinct protein components that disassemble at tunable pH levels, enabling targeted delivery of biologics.

bioRxiv · Apr 17, 2023Bioengineering