Author

C. Dobbins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Assay:protein structure· 2 Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1

Frequent Co-Authors

N. P. King· 3 shared A. Hand· 2 shared M. Ahlrichs· 2 shared M. C. Miranda· 2 shared A. Addetia· 1 shared A. C. Walls· 1 shared A. Dosey· 1 shared A. E. Burtner· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBiochemistry

N. P. King

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Author profile →

3 papers

Recent·Most cited

De novo design of protein minibinder agonists of TLR3

C. S. Adams, H. Kim, A. E. Burtner, D. S. Lee, C. Dobbins, C. Criswell, B. Coventry, H. M. Kim, N. P. King

This study designs protein minibinders that act as agonists for TLR3, showing nanomolar binding and biological activity in cell lines.

bioRxiv · Apr 17, 2024Biochemistry

Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV

C. W. Chao, K. R. Sprouse, M. C. Miranda, N. J. Catanzaro, M. L. Hubbard, A. Addetia, C. Stewart, J. T. Brown, A. Dosey, A. Valdez, R. Ravichandran, G. G. Hendricks, M. Ahlrichs, C. Dobbins, A. Hand, , N. P. King

This study develops MERS-CoV vaccines using a protein nanoparticle platform, showing they induce strong neutralizing antibodies and protect mice against MERS-CoV challenge.

bioRxiv · Mar 13, 2024Immunology

Computational design of non-porous, pH-responsive antibody nanoparticles

E. C. Yang, R. Divine, M. C. Miranda, A. J. Borst, W. Sheffler, J. Z. Zhang, J. Decarreau, A. Sarajovi, M. Abedi, N. Goldbach, M. Ahlrichs, C. Dobbins, A. Hand, S. Cheng, M. Lamb, , D. Baker

This paper designs pH-responsive antibody nanoparticles with three distinct protein components that disassemble at tunable pH levels, enabling targeted delivery of biologics.

bioRxiv · Apr 17, 2023Bioengineering