Author

R. T. Wyatt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:non-human primate· 2 Assay:structural biology· 1

Frequent Co-Authors

A. B. Ward· 1 shared A. Finzi· 1 shared A. Mileant· 1 shared B. Murrell· 1 shared B. Nogal· 1 shared B. von Bredow· 1 shared C. A. Cottrell· 1 shared C. Havenar-Daughton· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

A. B. Ward

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2 papers

Recent·Most cited

Structurally related but genetically unrelated antibody lineages converge on an immunodominantHIV-1 Env neutralizing determinant following trimer immunization

S. Aljedani, T. J. Liban, K. Tran, G. Phad, S. Singh, V. Dubrovskaya, P. Pushparaj, P. Martinez-Murillo, J. Rodarte, A. Mileant, V. Mangala, R. Kinzelman, S. O'Dell, J. R. Mascola, K. K. Lee, , M. Pancera

The paper analyzes monoclonal antibodies from vaccinated non-human primates to identify a conserved immunodominant epitope in HIV-1 Env and how different lineages target it for potent neutralization.

bioRxiv · Apr 9, 2021Biochemistry

Vaccine-induced protection from homologous Tier 2 simian-human immunodeficiency virus challenge in nonhuman primates

M. G. Pauthner, J. P. Nkolola, C. Havenar-Daughton, B. Murrell, S. M. Reiss, R. Bastidas, J. Prevost, R. Nedellec, B. von Bredow, P. Abbink, C. A. Cottrell, D. W. Kulp, T. Tokatlian, B. Nogal, M. Bianchi, , D. R. Burton

This study shows that high serum neutralizing antibody titers from Env protein vaccination protect rhesus macaques from Tier 2 SHIV challenge, with ~1:500 ID50 titers providing over 90% protection.

bioRxiv · Oct 29, 2018Immunology