Author

P. Pushparaj

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

G. B. Karlsson Hedestam· 3 shared B. Murrell· 2 shared C. Kim· 2 shared D. J. Sheward· 2 shared L. Hanke· 2 shared A. Mileant· 1 shared B. M. Hällberg· 1 shared G. M. McInerney· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

G. B. Karlsson Hedestam

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural basis of Omicron neutralization by affinity-matured public antibodies

D. J. Sheward, P. Pushparaj, H. Das, C. Kim, S. Kim, L. Hanke, R. Dyrdak, G. M. McInerney, J. Albert, B. Murrell, G. B. Karlsson Hedestam, B. M. Hällberg

The paper identifies affinity-matured antibodies that neutralize SARS-CoV-2 Omicron with high potency and resolves their structure to explain cross-neutralization.

bioRxiv · Jan 3, 2022 · PreprintImmunology

Structurally related but genetically unrelated antibody lineages converge on an immunodominantHIV-1 Env neutralizing determinant following trimer immunization

S. Aljedani, T. J. Liban, K. Tran, G. Phad, S. Singh, V. Dubrovskaya, P. Pushparaj, P. Martinez-Murillo, J. Rodarte, A. Mileant, V. Mangala, R. Kinzelman, S. O'Dell, J. R. Mascola, K. K. Lee, , M. Pancera

The paper analyzes monoclonal antibodies from vaccinated non-human primates to identify a conserved immunodominant epitope in HIV-1 Env and how different lineages target it for potent neutralization.

bioRxiv · Apr 9, 2021Biochemistry

SARS-CoV-2 protein subunit vaccination elicits potent neutralizing antibody responses

M. Mandolesi, D. J. Sheward, L. Hanke, J. Ma, P. Pushparaj, L. Perez Vidakovics, C. Kim, K. Lore, X. Castro Dopico, J. M. Coquet, G. McInerney, G. B. Karlsson Hedestam, B. Murrell

This study shows that SARS-CoV-2 spike protein subunit vaccines induce strong neutralizing antibodies in mice and macaques, with high titers after a single dose or dose-sparing regimen.

bioRxiv · Jul 31, 2020Immunology