Author

R. Vaid

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Mendez· 2 shared C. Bartenhagen· 2 shared K. Thombare· 2 shared M. Fischer· 2 shared R. Burgos-Panadero· 2 shared T. Mondal· 2 shared A. A. Rehan· 1 shared A. Djos· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

A. Mendez

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Author profile →

2 papers

Recent·Most cited

METTL3 drives telomere targeting of TERRA lncRNA through m6A-dependent R-loop formation: a therapeutic target for ALT-positive neuroblastoma

R. Vaid, K. Thombare, A. Mendez, R. Burgos-Panadero, A. Djos, D. Jachimowicz, K. Ihrmark Lundberg, C. Bartenhagen, N. Kumar, C. Tummler, C. Sihlbom, S. Fransson, J. I. Johnsen, P. Kogner, T. Martinsson, , T. Mondal

This study shows METTL3 modifies TERRA lncRNA with m6A, promoting R-loop formation that targets TERRA to telomeres, and inhibiting METTL3 disrupts this process in ALT+ neuroblastoma cells.

Nucleic Acids Research · Mar 21, 2024Peer-reviewedCancer Biology

METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma

K. Thombare, R. Vaid, P. Pucci, A. Mendez, R. Burgos-Panadero, R. Ayyalusamy, A. A. Rehan, M. H. Baig, S. D. Nale, C. Bartenhagen, J. j. Dong, M. Fischer, S. D. Turner, T. Mondal

This study shows METTL3 and MYCN cooperate to maintain undifferentiated neural crest cells in neuroblastoma, and METTL3 inhibition promotes differentiation and chemosensitivity.

bioRxiv · Oct 6, 2023Cancer Biology