Author

T. Martinsson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

P. Kogner· 4 shared J. I. Johnsen· 3 shared S. Fransson· 3 shared C. Bartenhagen· 2 shared I. Adameyko· 2 shared J. Holmberg· 2 shared M. Fischer· 2 shared N. Baryawno· 2 shared

Activity by Year

2020-2024 · peak 2/yr

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10 top collaborators · 40 mutual co-author links

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4 shared papersCancer Biology

P. Kogner

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4 papers

Recent·Most cited

METTL3 drives telomere targeting of TERRA lncRNA through m6A-dependent R-loop formation: a therapeutic target for ALT-positive neuroblastoma

R. Vaid, K. Thombare, A. Mendez, R. Burgos-Panadero, A. Djos, D. Jachimowicz, K. Ihrmark Lundberg, C. Bartenhagen, N. Kumar, C. Tummler, C. Sihlbom, S. Fransson, J. I. Johnsen, P. Kogner, T. Martinsson, , T. Mondal

This study shows METTL3 modifies TERRA lncRNA with m6A, promoting R-loop formation that targets TERRA to telomeres, and inhibiting METTL3 disrupts this process in ALT+ neuroblastoma cells.

Nucleic Acids Research · Mar 21, 2024Peer-reviewedCancer Biology

Single-nuclei transcriptomes from human adrenal gland reveals distinct cellular identities of low and high-risk neuroblastoma tumors.

O. C. Bedoya-Reina, W. Li, M. Arceo, M. Plescher, P. Bullova, H. Pui, M. Kaucka, P. Kharchenko, T. Martinsson, J. Holmberg, I. Adameyko, Q. Deng, C. Larsson, C. Juhlin, P. Kogner, S. Schlisio

The paper identifies distinct cellular identities in low and high-risk neuroblastoma tumors using single-nuclei transcriptomes, linking them to clinical outcomes and age at diagnosis.

bioRxiv · Mar 26, 2021Cancer Biology

PPM1D is a neuroblastoma oncogene and therapeutic target in childhood neural tumors.

J. Milosevic, S. Fransson, M. Gulyas, G. Gallo-Oller, T. K. Olsen, D. Treis, M. Wickstrom, L. H. Elfman, B. Sveinbjornsson, F. Hertwig, C. Bartenhagen, S. Reinsbach, M. Wilhelm, F. Abel, N. Javanmardi, , P. Kogner

This study identifies PPM1D as an oncogene and therapeutic target in neuroblastoma by showing its role in p53 inactivation and tumor growth.

bioRxiv · Sep 4, 2020 · PreprintCancer Biology

Malignant Schwann cell precursors mediate intratumoral plasticity in human neuroblastoma

T. K. Olsen, J. Otte, S. Mei, P. Kameneva, A. Bjoerklund, E. Kryukov, Z. Hou, A. Johansson, E. Sundstroem, T. Martinsson, S. Fransson, J. I. Johnsen, P. Kogner, I. Adameyko, P. V. Kharchenko, N. Baryawno

The paper identifies a subpopulation of malignant Schwann cell precursor-like cells in neuroblastoma that connects adrenergic and mesenchymal tumor cells, suggesting intratumoral plasticity mechanisms.

bioRxiv · May 4, 2020 · PreprintCancer Biology