Author

R. van Domselaar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

U. Neogi· 2 shared A. Sonnerborg· 1 shared A. Sönnerborg· 1 shared A. Vegvari· 1 shared D. T. Njenda· 1 shared E. Saccon· 1 shared F. Mikaeloff· 1 shared K. Singh· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

U. Neogi

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2 papers

Recent·Most cited

Cytotoxic lymphocytes target HIV-1 Gag through granzyme M-mediated cleavage

E. Saccon, F. Mikaeloff, P. Figueras Ivern, A. Vegvari, A. Sonnerborg, U. Neogi, R. van Domselaar

This study shows that granzyme M from cytotoxic lymphocytes cleaves HIV-1 Gag, potentially controlling infection without killing infected cells.

bioRxiv · Feb 24, 2021Immunology

HIV-1 subtype C with PYxE insertion has enhanced binding of Gag-p6 to host cell protein ALIX and increased replication fitness

R. van Domselaar, D. T. Njenda, R. K. Rao, A. Sönnerborg, K. Singh, U. Neogi

This paper shows that HIV-1C with PYxE insertion enhances Gag-p6 binding to ALIX and increases replication fitness, reducing sensitivity to antiretroviral drugs.

bioRxiv · Jan 18, 2019Microbiology