Author

Rachael Thomas

Boston University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Michael D. BloweriD· 4 shared Emily SparagoiD· 2 shared Judith A. SharpiD· 2 shared Anne Aldrich· 1 shared Kaitlyn AlimentiiD· 1 shared Shawn M. LyonsiD· 1 shared Wei WangiD· 1 shared Wei WangiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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4 shared papersCell Biology

Michael D. BlowerORCID

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4 papers

Recent·Most cited

Using combined RNA/DNA short read sequencing to investigate allele-specific expression from the inactive X chromosome in human cells

Rachael Thomas, Michael D. Blower

The paper presents a method to assign SNPs to active or inactive X chromosomes using short read RNA and DNA sequencing, enabling allele-specific expression analysis in human cell lines without long read sequencing.

bioRxiv · May 24, 2026 · PreprintBioinformatics

Role of the SAF-A/HNRNPU ATPase and RGG domains in X chromosome inactivation, nuclear dynamics, transcription, splicing, and cell proliferation

Judith A. Sharp, Rachael Thomas, Emily Sparago, Wei Wang, Michael D. Blower

This study investigates the role of SAF-A's ATPase and RGG domains in nuclear processes, showing their involvement in XIST RNA maintenance, splicing, and cell proliferation.

bioRxiv · Dec 17, 2025 · PreprintCell Biology

Metal stress uncouples early pre-rRNA processing from ISR activation and reveals flexible checkpoints in human ribosome biogenesis

Anne Aldrich, Rachael Thomas, Michael D. Blower, Shawn M. Lyons

bioRxiv · Jul 14, 2025 · PreprintBiochemistry

Role of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation

Judith A. Sharp, Emily Sparago, Rachael Thomas, Kaitlyn Alimenti, Wei Wang, Michael D. Blower

This study investigates the role of SAF-A's SAP domain and its serines S14 and S26 in X inactivation, gene expression, splicing, and cell proliferation, finding they are critical for XIST RNA localization and cell proliferation but not gene expression or splicing.

PLoS Genetics · Jun 10, 2025Peer-reviewedCell Biology