Author

Judith A. Sharp

Boston UniversityORCID 0000-0001-7441-6218Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Emily SparagoiD· 2 shared Michael D. BloweriD· 2 shared Rachael Thomas· 2 shared Kaitlyn AlimentiiD· 1 shared Wei WangiD· 1 shared Wei WangiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

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2 shared papersCell Biology

Emily SparagoORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintDec 17, 2025

Role of the SAF-A/HNRNPU ATPase and RGG domains in X chromosome inactivation, nuclear dynamics, transcription, splicing, and cell proliferation

Judith A. Sharp, Rachael Thomas, Emily Sparago…·Michael D. Blower

This study investigates the role of SAF-A's ATPase and RGG domains in nuclear processes, showing their involvement in XIST RNA maintenance, splicing, and cell proliferation.

DOI 10.64898/2025.12.15.694381

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologyPLoS GeneticsPeer-reviewedJun 10, 2025

Role of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation

Judith A. Sharp, Emily Sparago, Rachael Thomas…·Michael D. Blower

This study investigates the role of SAF-A's SAP domain and its serines S14 and S26 in X inactivation, gene expression, splicing, and cell proliferation, finding they are critical for XIST RNA localization and cell proliferation but not gene expression or splicing.

5 citations

humanDNA methylation

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