NeurosciencebioRxivPreprint
The exocyst is an insulin-sensitive regulator of amyloid precursor protein trafficking and amyloid-beta generation in neurons
Chantell Balaan, Geetika Y. Patwardhan, Rachel K Sachs…·Ben Fogelgren
The paper shows the exocyst regulates APP trafficking and amyloid-beta generation in neurons, with insulin signaling shifting exocyst activity away from APP to GLUT4.