Author

Rafael Barrero

Spanish National Cancer Research Centre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Blanca Rosas-PéreziD· 2 shared Bruno SáinziD· 2 shared Carmen E. GuerraiD· 2 shared Elena Zamorano-DomíngueziD· 2 shared Juan Carlos López-GiliD· 2 shared Mariano BarbacidiD· 2 shared Pian SuniD· 2 shared Silvia Jiménez-Parrado· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Blanca Rosas-PérezORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

High-fat diet imprints a macrophage-tumor CAMP-P2RX7 axis driving pancreatic cancer initiation, plasticity and metastasis

Ana Galván-del-Rey, Juan Carlos López-Gil, Livia Archibugi, Sonia Alcalá, Julie Earl, Michele Bevere, Antonio Agostini, Aleix Noguera‐Castells, Beatriz Parejo-Alonso, Alba Royo-García, Kyra Fraser, Pian Sun, Elena Zamorano-Domínguez, Blanca Rosas-Pérez, Rafael Barrero, , Carmen Guerra

This study identifies a diet-imprinted macrophage-tumor circuit driven by the CAMP-P2RX7 axis that promotes pancreatic cancer initiation, plasticity, and metastasis.

bioRxiv · Feb 14, 2026 · PreprintCancer Biology

A TARGETED COMBINATION THERAPY ACHIEVES EFFECTIVE PANCREATIC CANCER REGRESSION AND PREVENTS TUMOR RESISTANCE

Vasiliki Liaki, Sara Barrambana, Myrto Kostopoulou, Carmen G. Lechuga, Elena Zamorano-Domínguez, Domingo Acosta, Lucía Morales-Cacho, Ruth Álvarez, Pian Sun, Blanca Rosas-Pérez, Rafael Barrero, Silvia Jiménez-Parrado, Alejandra López-García, Marta San Roman, Juan Carlos López-Gil, , Mariano Barbacid

This paper shows that combining three KRAS signaling pathway inhibitors effectively regresses pancreatic tumors and prevents resistance in preclinical models.

Proceedings of the National Academy of Sciences · Dec 2, 2025Peer-reviewedCancer Biology