Tri-Functional CRISPR Screen Reveals Overexpression of QDR2 and QDR3 Transporters Increase Fumaric Acid Production in Kluyveromyces marxianus
Mackenzie Thornbury, Raha Parvizi Omran, Lalit Kumar, Adrien Knoops, Raghad Abushahin, Malcolm S. Whiteway, Vincent J. J. Martin
The paper uses a trifunctional CRISPR screen to identify gene perturbations that enhance fumaric acid tolerance and production in Kluyveromyces marxianus.
ACS Synthetic Biology · Nov 24, 2025Peer-reviewedSynthetic Biology