A Ubiquitin network safeguards cell identity by continuously degrading stem-cell related translational machinery
Salwa Danial, Raya Ghanem, Muhammad Makhzumy, Avital Oknin Vaisman, Eliya Bitman-Lotan, Fabian Glaser, Jelly Soffers, Jesslyn C. Henriksen, Avital Sarusi-Portuguez, Olivia S. Rissland, Ryan D. Mohan, Ayala Shiber, Amir Orian
The paper identifies a ubiquitin network that maintains enterocyte identity by degrading stem-cell related translational machinery, which is disrupted with aging.
bioRxiv · Mar 8, 2026 · PreprintCell Biology