Author

Qi‐En Wang

The Ohio State UniversityORCID 0000-0002-3759-2148Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Na Li· 2 shared Alexis Bernat· 1 shared Balázs BognáriD· 1 shared Brendan Harty· 1 shared David E. CohniD· 1 shared David M. O’MalleyiD· 1 shared Dehua PeiiD· 1 shared Gabriela S. Vendrell· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

Na Li

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

STN1 upregulation promotes PARPi resistance in BRCA2-deficient cancer cells via replication fork protection and suppression of ssDNA gap formation

Zubair Ahmed Laghari, Na Li, Serdar Gayybov, Qi‐En Wang, Weihang Chai

This study identifies STN1 as a factor promoting PARPi resistance in BRCA2-deficient cancer cells by stabilizing replication forks and reducing ssDNA gaps.

NAR Cancer · Jul 27, 2026Peer-reviewedCancer Biology

Intracellular Delivery of Peptides and Proteins with an Engineered Membrane Translocation Domain

Prabhat Bhat, Heba Salim, Jeremy L. Ritchey, Na Li, Brendan Harty, Thomas Patel, Jing Zhao, Qi‐En Wang, Virginia L. King, Louis A. Tartaglia, Jenő Gyuris, Dehua Pei

This paper develops an engineered membrane translocation domain (MTD4) that enables efficient intracellular delivery of peptides and proteins, demonstrating its effectiveness in vitro and in vivo.

ACS Chemical Biology · Jul 1, 2026Peer-reviewedBioengineering

HO-3867 mediated modulation of Extracellular vesicles and Tumor microenvironment: A novel immunotherapeutic strategy for ovarian cancer

Ganesh Yadagiri, Lakshmi Narasimhan Chakrapani, Shyam Sundaram, Jessica Velasquez, Tiffany L. Hughes, Gabriela S. Vendrell, Balázs Bognár, Qi‐En Wang, David M. O’Malley, David E. Cohn, Karuppaiyah Selvendiran, Kalpana Deepa Priya Dorayappan

This study shows that HO-3867 and bevacizumab together reduce ascites, limit tumor spread, and enhance anti-tumor immunity in ovarian cancer models by modulating extracellular vesicles and immune cells.

bioRxiv · May 16, 2025 · PreprintCancer Biology

XPC loss-of-function triggers melanomagenesis through CDKN2A downregulation

Vipin Shankar Chelakkot, Kiara Thomas, Todd Romigh, Alexis Bernat, Reina Samuel, Nihit Goli, Pooja H. Rambhia, Sairekha Ravichandran, Qi‐En Wang, Kevin D. Cooper, Pauline Funchain, Ying Ni, Joshua Arbesman

This study identifies an XPC variant that promotes melanomagenesis by downregulating CDKN2A through promoter binding, independent of its nucleotide excision repair function.

bioRxiv · Apr 3, 2025 · PreprintCancer Biology