Structure of human lymphoid-specific helicase HELLS in its autoinhibitory state
Gundeep Kaur, Ren Ren, Jisun Lee, John R. Horton, Xing Zhang, Yang Gao, Taiping Chen, Xiaodong Cheng
This paper determines the structure of HELLS in its autoinhibitory state and shows how CDCA7 and DNA activate it.
bioRxiv · Dec 6, 2025 · PreprintMolecular Biology