Renee J. Tamming

Single-molecule identification of the target RNAs of different RNA binding proteins simultaneously in cells

The paper introduces TRIBE-STAMP, a method to identify target RNAs of multiple RNA-binding proteins simultaneously at the single-molecule level in cells, revealing that individual mRNAs can be bound by multiple YTHDF proteins.

Atrx deletion in neurons leads to sexually-dimorphic dysregulation of miR-137 and spatial learning and memory deficits

This study shows that deleting Atrx in mouse forebrain neurons causes male-specific spatial memory deficits linked to miR-137 dysregulation and synaptic abnormalities.