Pengfei Song

Stabilizing gas in aqueous liquids with metal-organic frameworks for persistent acoustic transduction

This paper demonstrates the stabilization of gas in aqueous environments using metal-organic frameworks to enable persistent acoustic transduction for long-term ultrasound-biological interfacing.

3D-PAULM: Integrated Photoacoustic Tomography and Ultrasound Localization Microscopy for Multiparametric Brain and Tumor Imaging

This paper introduces 3D-PAULM, an integrated imaging platform that combines photoacoustic tomography and ultrasound localization microscopy to enable multiparametric brain and tumor imaging.

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

This study establishes and validates an awake longitudinal fUS-ULM-fULM framework in mice over five months, showing no significant longitudinal drift and no memory impairment or chronic neuroinflammation.

Whole-body Super-resolution Functional and Molecular Imaging with Panoramic Photoacoustic-Ultrasound Tomography

This paper introduces a panoramic PA-US imaging platform that improves resolution and accuracy in whole-body functional and molecular imaging.

Three-Dimensional Photoacoustic Tomography with Ultrasound Localization Priors

This paper introduces 3D-PAULMprior, a method that improves 3D photoacoustic tomography by integrating ultrasound localization priors, enhancing resolution and accuracy in vascular imaging and oxygen saturation estimation.

Microbubble Track-based Functional Ultrasound Localization Microscopy in Awake Mice

This paper develops a microbubble track-based method to improve functional ultrasound localization microscopy's sensitivity in awake mice without sacrificing spatial resolution.

Microbubble Backscattering Intensity Improves the Sensitivity of Three-dimensional (3D) Functional Ultrasound Localization Microscopy (fULM)

This paper introduces backscattering fULM (B-fULM) to improve 3D functional ultrasound imaging sensitivity by integrating microbubble amplitude with count-based localization.

Advanced deep-tissue imaging and manipulation enabled by biliverdin reductase knockout.

This paper develops NIR imaging and optogenetic tools using Blvra-/- knockout to enhance light-controlled transcription and in vivo glucose regulation.

Improved Microbubble Tracking for Super-Resolution Ultrasound Localization Microscopy using a Bi-Directional Long Short-term Memory Neural Network

This paper introduces a deep learning method using a bi-directional LSTM network to improve microbubble tracking in ULM, validated on simulations, phantoms, and in vivo mouse and rat brains.

Combined Nanodrops Imaging and Ultrasound Localization Microscopy for Detecting Intracerebral Hemorrhage

This paper introduces a combined imaging technique using ultrasound localization microscopy and nanodrop imaging to detect intracerebral hemorrhage in rodent models.

Capillary-scale Microvessel Imaging with High-frequency Ultrasound Localization Microscopy in Mouse Brain

This paper demonstrates that high-frequency ultrasound localization microscopy improves microvascular imaging fidelity and efficiency in mouse brains.

SARS-COV-2 induces blood-brain barrier and choroid plexus barrier impairments and vascular inflammation in mice

This study shows SARS-CoV-2 causes blood-brain barrier and choroid plexus barrier damage and vascular inflammation in mice, contributing to neurological complications.

Super-resolution ultrasound imaging of cerebrovascular impairment in a mouse model of Alzheimer's disease

This study uses ultrasound localization microscopy to image cerebrovascular impairments in a mouse model of Alzheimer's disease, finding early functional vascular changes precede structural derangements.

Aging-related cerebral microvascular changes visualized using Ultrasound Localization Microscopy in the living mouse

This study uses Ultrasound Localization Microscopy to quantify aging-related changes in cerebral microvascular dynamics in living mice, finding reduced blood velocity, increased tortuosity, and decreased blood volume in the cortex.

Changes in spinal cord hemodynamic reflect modulation of spinal network with different parameters of epidural stimulation

This study uses functional ultrasound imaging to show that spinal cord hemodynamic responses to epidural stimulation reflect changes in spinal circuitry organization based on stimulation parameters.