Author

Richard M. Murray

Primary ORCID profile (0000-0002-5785-7481 · 71 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Richard M. MurrayiD71 papers · California Institute of Technology

Biology Disciplines

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Synthetic Biology· 2 Bioengineering· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:E. coli· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Approach:optimal transport· 1

Frequent Co-Authors

Yong Y. Wu· 3 shared Julia Khandurina· 2 shared Stephen Van Dien· 2 shared Harish Nagarajan· 1 shared Hirokazu Sato· 1 shared Hongjun Huang· 1 shared Nikolai Matni· 1 shared Phuc H.B. Nguyen· 1 shared

Activity by Year

2014-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersSynthetic Biology

Yong Y. Wu

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Author profile →

4 papers

Recent·Most cited

System-level studies of a cell-free transcription-translation platform for metabolic engineering

Yong Y. Wu, Hirokazu Sato, Hongjun Huang, Stephanie J. Culler, Julia Khandurina, Harish Nagarajan, Tae Hoon Yang, Stephen Van Dien, Richard M. Murray

The paper demonstrates the use of a cell-free TX-TL system to rapidly engineer and optimize the BDO pathway for improved product yield.

bioRxiv · Aug 3, 2017 · PreprintBioengineering

Design Space Exploration of the Violacein Pathway in Escherichia coli Based Transcription Translation Cell-Free System (TX-TL)

Phuc H.B. Nguyen, Yong Y. Wu, Shaobin Guo, Richard M. Murray

The paper explores the design space of the violacein pathway in an E. coli-based TX-TL system, identifying optimal enzyme expression levels for improved product yield.

bioRxiv · Jan 26, 2016 · PreprintSynthetic Biology

Prototyping 1,4-butanediol (BDO) biosynthesis pathway in a cell-free transcription-translation (TX-TL) system

Yong Y. Wu, Stephanie Culler, Julia Khandurina, Stephen Van Dien, Richard M. Murray

This study uses a cell-free TX-TL system to prototype and optimize the 1,4-butanediol biosynthesis pathway by testing enzyme expression levels and identifying rate-limiting steps.

bioRxiv · Apr 9, 2015 · PreprintSynthetic Biology

Synthesizing Combination Therapies for Evolutionary Dynamics of Disease for Nonlinear Pharmacodynamics

Vanessa Jonsson, Nikolai Matni, Richard M. Murray

The paper extends a previous algorithm for designing combination therapies by modeling nonlinear pharmacodynamics using piecewise linear approximations and optimal controller synthesis for positive systems.

bioRxiv · Sep 21, 2014 · PreprintEvolutionary Biology