Author

Robert Heler

Rockefeller University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alejandro ChaveziD· 1 shared Bradley J. MerrilliD· 1 shared George McDonald ChurchiD· 1 shared Leslyn A. HanakahiiD· 1 shared Luciano A. MarraffiniiD· 1 shared Matthew S. MacDougalliD· 1 shared Maureen R. Regan· 1 shared Nan Cher YeoiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Alejandro ChavezORCID

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Author profile →

1 paper

Recent·Most cited

Enhanced bacterial immunity and mammalian genome editing via RNA polymerase-mediated dislodging of Cas9 from double strand DNA breaks.

Ryan Clarke, Robert Heler, Matthew S. MacDougall, Nan Cher Yeo, Alejandro Chavez, Maureen R. Regan, Leslyn A. Hanakahi, George McDonald Church, Luciano A. Marraffini, Bradley J. Merrill

This paper shows that RNA polymerase can dislodge Cas9 from DNA breaks, improving genome editing and bacterial immunity by increasing mutagenesis and phage resistance.

Molecular Cell · Jul 1, 2018Peer-reviewedMolecular Biology