Author

Leslyn A. Hanakahi

University of Illinois ChicagoORCID 0000-0001-8605-009XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alejandro ChaveziD· 1 shared Bradley J. MerrilliD· 1 shared George McDonald ChurchiD· 1 shared Luciano A. MarraffiniiD· 1 shared Matthew S. MacDougalliD· 1 shared Maureen R. Regan· 1 shared Nan Cher YeoiD· 1 shared Robert Heler· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Alejandro ChavezORCID

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1 paper

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedJul 1, 2018

Enhanced bacterial immunity and mammalian genome editing via RNA polymerase-mediated dislodging of Cas9 from double strand DNA breaks.

Ryan Clarke, Robert Heler, Matthew S. MacDougall…·Bradley J. Merrill

This paper shows that RNA polymerase can dislodge Cas9 from DNA breaks, improving genome editing and bacterial immunity by increasing mutagenesis and phage resistance.

143 citationstop 2%

bacteria (other)human

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