Acute infectious mononucleosis generates persistent, functional EBNA-1 antibodies with high cross-reactivity to alpha crystalline beta
Krishna Kumar Ganta, Margaret M. McManus, Ross Blanc, Qixin Wang, Wonyeong Jung, Robin Brody, Mary N Carrington, Robert Paris, Sumana Chandramouli, Ryan P. McNamara, Katherine Luzuriaga
The paper investigates EBNA-1 specific antibodies in IM patients, finding persistent functional antibodies with cross-reactivity to CRYAB and association with MS risk alleles.
Cell Reports · May 1, 2025Peer-reviewedImmunology