Mary N Carrington

This paper introduces scTAPAS, a method to reconstruct donor genotypes from scRNA-seq data, enabling eQTL and HLA-TCR analysis without conventional genotyping.

This study identifies MHC-II antigens from Mycobacterium tuberculosis using mass spectrometry and evaluates mRNA vaccine immunogens to enhance T cell recognition.

PathMHC improves identification of pathogen-derived MHC peptides for vaccine targets by combining computational analysis with targeted mass spectrometry.

The paper investigates EBNA-1 specific antibodies in IM patients, finding persistent functional antibodies with cross-reactivity to CRYAB and association with MS risk alleles.

The paper identifies a Neandertal introgressed haplotype in the OAS1 gene associated with increased risk of severe COVID-19 and shows it impairs SARS-CoV-2 clearance through genetic regulation of OAS1 expression.

The paper investigates host genetic variations in MX1, CCR5Δ32, and MHC class I alleles in HIV+ non-controllers on ART and finds associations with HIV reservoir size.

The paper investigates the association between LILRB2-HLA-B interaction strength and psoriasis susceptibility using GWAS data, finding an inverse relationship with risk.

This paper develops a peptidome-wide association study to identify HIV epitopes linked to viral load, revealing patient-specific epitope repertoires that explain HLA-related variation in HIV control.