Ryan P. McNamara

This study compares antibody responses between two mRNA vaccines, finding that sa-mRNA elicited sustained, activating antibodies with broader coverage against SARS-CoV-2 variants.

This paper designs and evaluates nanoparticle vaccines with optimized linkers to enhance cross-reactive antibody responses against coronaviruses and other viral families.

The paper designs multiclade coronavirus spike immunodominant domain nanoparticles that elicit broad antibody responses against multiple EhCoVs and SARS-CoV-2 variants in mice.

The paper identifies distinct antibody-based signatures and functionalities in latent and active pediatric tuberculosis, highlighting differences in humoral immune responses that may inform diagnostic and therapeutic strategies.

The paper investigates EBNA-1 specific antibodies in IM patients, finding persistent functional antibodies with cross-reactivity to CRYAB and association with MS risk alleles.

The paper investigates immune correlates of early Mtb clearance in TB household contacts, finding that BCG vaccination is linked to enhanced innate immune responses rather than adaptive immunity.

This study compares antibody responses to SARS-CoV-2 spike protein between monovalent XBB.1.5 and bivalent WT/BA.5 mRNA vaccines, finding the monovalent vaccine induces higher and more durable antibody responses.

This study identifies compartment-specific antibody correlates of protection against SARS-CoV-2 Omicron in macaques, showing neutralizing antibodies in serum and antibody-dependent cellular phagocytosis in bronchiolar lavage are strongest correlates.