Hydrogen sulfide dynamically upregulates copper uptake and localization
Jutta Diessl, Joseph V. Roman, Roshan Kumar, David A. Hanna, Aaron C. Sue, Andrew Crawford, Romika Shokohi, Anya Parikh, Ajith Pattammattel, Andrew M. Kiss, Kewei Zhao, Ajay Larkin, Yibo Fu, Alex Guo, Timothy Durham, , Ruma V. Banerjee
This study shows hydrogen sulfide increases copper uptake and localization in cells, with copper primarily in the Cu2+ state, using the ZNT1 transporter for import and ATP7A for export.
bioRxiv · Jul 31, 2026 · PreprintCell Biology