Rosa Portero Migueles

The paper identifies two thresholds of Brachyury expression in NMPs that determine lineage potential and axis-forming ability in vitro.

The paper introduces a toolkit to analyze cell identity patterning by comparing cells to their neighbors, revealing Notch-dependent heterogeneity in neuromesodermal progenitors.

SyNPL uses Synthetic Notch technology to monitor and manipulate cell-cell interactions in pluripotent stem cells and embryos, enabling synthetic patterning of cell fates.

This study shows that competence to epithelialise and differentiate in pluripotent cells is regulated by Tcf15, linking these processes through integrin alpha3 upregulation.

Nessys provides a method for accurate 3D nuclear segmentation in dense, heterogeneous tissues and tracks cell interactions during differentiation.

This study shows N-cadherin stabilizes neural identity by reducing anti-neural signals during differentiation.