The INO80 ATP-dependent chromatin remodelling complex alleviates stalled Polymerase II to promote non-coding RNA transcription termination.
Sara Luzzi, Ugo Szachnowski, Sarah Greener, Kenny Schumacher, Stuart Fulton, Chloe Walton, Camille Gautier, Kang Hoo Han, Jack Darke, Rossana Piccinno, Anne Lafon, B. Franklin Pugh, Didier Devys, Làszlò Tora, Antonin Morillon, Manolis Papamichos‐Chronakis
This study shows the INO80 complex helps RNA Polymerase II move past stalled positions, aiding non-coding RNA termination in yeast.
bioRxiv · Mar 2, 2020 · PreprintMolecular Biology