Author

Ruben Fritsche

University of Kassel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Kirstin GutekunstiD· 2 shared Marius L. TheuneiD· 2 shared Marko BoehmiD· 2 shared Alexander MakowkaiD· 1 shared Anika WiegardiD· 1 shared Bettina SiebersiD· 1 shared Carmen Peraglie· 1 shared Christopher BräseniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Kirstin GutekunstORCID

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2 papers

Recent·Most cited

Story about honest mistakes: The cyanobacterium Synechocystis has a promiscuous Entner-Doudoroff (ED) aldolase but no functional ED pathway.

Ravi Shankar Ojha, Marius L. Theune, Ruben Fritsche, Alexander Makowka, Marko Boehm, Carmen Peraglie, Christopher Bräsen, Jacky L. Snoep, Martin Hagemann, Bettina Siebers, Kirstin Gutekunst

This study revisits the claim of the Entner-Doudoroff pathway in Synechocystis, showing that while the aldolase is present, the full pathway is absent due to missing enzymes and experimental errors.

bioRxiv · Jul 23, 2026 · PreprintMicrobiology

Easy-to-use whole-genome sequencing workflows and standardized practices to uncover hidden genetic variation in Synechocystis PCC 6803 wild-type and knock-out strains

Marius L. Theune, Ruben Fritsche, Niklas Kueppers, Marko Boehm, Petra Kolkhof, Florian Paul, Ovidiu Popa, Ellen Oldenburg, Anika Wiegard, Ilka Maria IM Axmann, Kirstin Gutekunst

This paper develops workflows for whole-genome sequencing to identify genetic variation in Synechocystis strains and highlights the importance of strain validation in knock-out studies.

bioRxiv · Apr 15, 2026 · PreprintMicrobiology