The non-coding facet of Pink1 mRNA regulates mitochondria homeostasis
Xiaofen Wu, Yuying Liu, Ruimiao Ma, Hongye Wang, Ruqi Fan, Hao Wang, Weili Yang, Xiaojiang Li, Guoliang Xu, Hong Cheng, Ping Hu
The study shows that non-coding Pink1 mRNA regulates mitochondria homeostasis by interacting with YME1L1 to modulate Opa1 processing, independent of its coding function.
bioRxiv · Jan 6, 2026 · PreprintCell Biology