Author

Ruocheng Shan

Children's National

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:Hi-C· 1

Frequent Co-Authors

Wei LiiD· 2 shared Derek PetersiD· 1 shared Fei TengiD· 1 shared Han ZhangiD· 1 shared Jian PengiD· 1 shared Lumen ChaoiD· 1 shared Shengnan WangiD· 1 shared Tongyu Sun· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioinformatics

Wei LiORCID

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2 papers

Recent·Most cited

Modeling CRISPR-Cas13d on-target and off-target effects using machine learning approaches

Xiaolong Cheng, Zexu Li, Ruocheng Shan, Zihan Li, Shengnan Wang, Wenchang Zhao, Han Zhang, Lumen Chao, Jian Peng, Fei Teng, Wei Li

The paper develops DeepCas13, a deep learning model to predict CRISPR-Cas13d gRNA on-target activity and off-target viability effects, improving accuracy for RNA editing applications.

Nature Communications · Feb 10, 2023Peer-reviewedBioinformatics

Multi-omics analysis of chromatin accessibility and interactions with transcriptome by HiCAR

Xiaolin Wei, Xiang Yu, Ruocheng Shan, Derek Peters, Tongyu Sun, Xin Lin, Wei Li, Yarui Diao

The paper introduces HiCAR, a method that simultaneously assesses chromatin accessibility, interactions, and transcriptome in low-input samples, revealing 46,792 cis-regulatory interactions in H1 hESCs.

bioRxiv · Nov 2, 2020 · PreprintGenomics