Deconstruction of the retrosplenial granular cortex for social behavior in the mouse model of fragile X syndrome
Huifang Shang, Ruonan Cai, Hao Sun, Tao Sheng, Yan‐Na Lian, Li Liu, Wei Chen, Lixia Gao, Han Xu, Chen Zhang, Jianhong Luo, Xinjian Li, Xiang‐Yao Li
The paper identifies reduced social-related neuronal activity in the retrosplenial granular cortex (RSG) of Fmr1-KO mice, leading to social novelty deficits and suggests RSG manipulation as a potential therapeutic strategy.
bioRxiv · Jan 24, 2021 · PreprintNeuroscience