Author

Ryan B. Smit

University of Calgary

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Brian T Lu· 1 shared Chandrasekhar GopalakrishnaniD· 1 shared Chris WangiD· 1 shared Clayton M. DilksiD· 1 shared Dave HanseniD· 1 shared Erik C. AnderseniD· 1 shared Hilary RacheriD· 1 shared John S. GilleardiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Brian T Lu

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2 papers

Recent·Most cited

Interactions of C. elegans -tubulins with the microtubule inhibitor albendazole

Linda M. Pallotto, Clayton M. Dilks, Ye‐Jean Park, Ryan B. Smit, Brian T Lu, Chandrasekhar Gopalakrishnan, John S. Gilleard, Erik C. Andersen, Paul E. Mains

The paper investigates the role of C. elegans β-tubulin genes in albendazole resistance, finding that tbb-2 modifies sensitivity and ben-1 mutations primarily confer resistance.

bioRxiv · Feb 27, 2022 · PreprintGenetics

Reduction of Derlin activity suppresses Notch-dependent tumours in the C. elegans germ line

Ramya Singh, Ryan B. Smit, Xin Wang, Chris Wang, Hilary Racher, Dave Hansen

The paper shows that reducing Derlin activity suppresses Notch-dependent over-proliferation in C. elegans germline, suggesting a role for ER stress and the UPR in mitigating Notch gain-of-function effects.

PLoS Genetics · Sep 23, 2021Peer-reviewedGenetics