Acyloxyacyl Hydrolase is a Host Determinant of Gut Microbiome-Mediated Pelvic Pain
Afrida Rahman-Enyart, Wen‐Bin Yang, Ryan E. Yaggie, Bryan A. White, Michael E. Welge, Loretta Sue Auvil, Matthew S. Berry, Colleen Bushell, John M. Rosen, Charles N. Rudick, Anthony J. Schaeffer, David J. Klumpp
This study shows AOAH deficiency causes gut dysbiosis and pelvic pain in mice, suggesting AOAH regulates microbiota and that microbiota may be a therapeutic target for IC/BPS.
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · Jul 28, 2021Peer-reviewedSystems Biology