Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation
Takashi Hotta, Morgan L. Pimm, Ezekiel C. Thomas, Yang Yue, Patrick Ryan DeLear, Lynne Blasius, Michael A. Cianfrocco, Morgan E. DeSantis, Ryota Horiuchi, Takumi Higaki, David Sept, Ryoma Ohi, Kristen J. Verhey
The paper investigates the accessibility of the α-tubulin C-terminal tail (Y-CTT) and finds it is regulated by microtubule lattice conformation through nucleotide state and MAP interactions.
eLife · Feb 9, 2026Peer-reviewedCell Biology