Yang Yue

Shepherding by biased diffusion organizes diffusible proteins on microtubules

The paper demonstrates that motors can shepherd diffusive proteins on microtubules through biased diffusion, revealing a mechanism for spatial patterning without direct binding.

CLASP2 promotes repair of kinesin-1 damage to the microtubule lattice

This study identifies CLASP2 as a factor that facilitates microtubule repair in response to damage caused by kinesin-1 motor proteins.

MATCAP1 preferentially binds an expanded tubulin conformation to generate detyrosinated and ?C2 a-tubulin

This study investigates how MATCAP1 binds to expanded microtubule conformations to generate detyrosinated and ΔC2 α-tubulin modifications.

Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation

The paper investigates the accessibility of the α-tubulin C-terminal tail (Y-CTT) and finds it is regulated by microtubule lattice conformation through nucleotide state and MAP interactions.

Kif6 regulates cilia motility and polarity in brain ependymal cells

The paper investigates the role of Kif6 in ependymal cilia motility and polarity, finding that its loss causes decreased cilia movement and hydrocephalus in mice.

Neurexin and Frizzled signaling intercept axonal-transport at microtubule minus-ends to control synapse formation

The paper identifies VAB-8/KIF26 as a key molecule mediating synaptic cargo delivery at microtubule minus-ends, linking Neurexin and Frizzled signaling to synapse formation in C. elegans.