Author

S. A. Abdul Rehman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Knebel· 2 shared C. Cazzaniga· 1 shared C. Johnson· 1 shared D. Svergun· 1 shared E. Di Nisio· 1 shared F. Lamoliatte· 1 shared L. A. Armstrong· 1 shared M. Muqit· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

A. Knebel

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMar 5, 2023

Discovery and characterization of non-canonical E2 conjugating enzymes

S. A. Abdul Rehman, E. Di Nisio, C. Cazzaniga…·V. De Cesare

The paper identifies and characterizes non-canonical E2 conjugating enzymes that ubiquitylate serine and threonine instead of lysine, revealing their target substrate and catalytic mechanism.

DOI 10.1101/2023.03.05.531151

humanproteomics

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BiochemistrybioRxivJan 27, 2021

Mechanism of activation and regulation of Deubiquitinase activity in MINDY1 and MINDY2

S. A. Abdul Rehman, L. A. Armstrong, S. M. Lange…·Y. Kulathu

This paper reveals the mechanism of MINDY1 and MINDY2 deubiquitinase activity, showing how substrate interaction relieves autoinhibition and enables cleavage of K48-linked ubiquitin chains.

DOI 10.1016/j.molcel.2021.08.024

structural biologyexperimental assay

𝕏 PostBluesky