Author

S. A. Leachman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

A. W. Lund· 2 shared J. Femel· 2 shared C. Hill· 1 shared D. Murugan· 1 shared H. du Bois· 1 shared I. D. Dryg· 1 shared J. L. Booth· 1 shared K. White· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

A. W. Lund

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2 papers

Recent·Most cited

T cell Egress via Lymphatic Vessels Limits the Intratumoral T cell Repertoire in Melanoma

M. M. Steele, I. D. Dryg, D. Murugan, J. Femel, H. du Bois, C. Hill, S. A. Leachman, Y. H. Chang, L. M. Coussens, A. W. Lund

The paper shows that T cell egress via lymphatic vessels limits intratumoral T cell diversity, and that CXCR4 inhibition enhances T cell retention and improves immunotherapy response.

bioRxiv · May 30, 2022 · PreprintImmunology

Quantitative multiplex immunohistochemistry reveals inter- and intra-patient lymphovascular and immune heterogeneity in primary cutaneous melanoma

J. Femel, J. L. Booth, T. G. Asnaashari, S. A. Leachman, T. Tsujikawa, K. White, Y. H. W. Chang, A. W. Lund

This paper uses quantitative multiplex immunohistochemistry to analyze lymphovascular and immune heterogeneity in primary cutaneous melanoma, finding that vessel subtypes correlate with immune infiltration and metastatic risk.

bioRxiv · Oct 8, 2021Cancer Biology