MicrobiologybioRxiv
A novel sialic acid-binding adhesin present in multiple species contributes to the pathogenesis of infective endocarditis
M. O. Gaytan, A. K. Singh, S. A. Woodiga…·S. J. King
This study identifies a novel sialic acid-binding adhesin, AsaA, in IE-causing bacteria that contributes to pathogenesis by binding platelets through sialic acid, expanding the known role of sialic acid as a receptor in bacterial-platelet interactions.
DOI 10.1371/journal.ppat.1009222