Signal Inhibitory Receptor on Leukocytes-1 recognizes S100 proteins
M. Rumpret, H. J. von Richthofen, M. van der Linden, G. H. A. Westerlaken, C. Talavera Ormeno, T. Y. Low, H. Ovaa, L. Meyaard
This study identifies S100 proteins as ligands for the inhibitory receptor SIRL-1, showing that SIRL-1 suppresses neutrophil ROS production via binding to S100A6.
bioRxiv · May 14, 2021Immunology